抱石莲质量标准研究

摘要

[目的] 研究药材抱石莲的显微特征、理化鉴别、水分、总灰分、酸不溶性灰分、醇溶性浸出物,为制定抱石莲药材的质量标准提供依据.[方法] 采用2005年版规定方法.[结果] 对抱石莲的显微特征进行了描述.理化鉴别结果,抱石莲药材醇提取物与醋酐-浓硫酸、氯仿-浓硫酸、冰醋酸-乙酰氯等试剂反应均呈阳性.抱石莲药材水分的平均含量为11.98%;总灰分平均含量为7.83%,酸不溶性灰分的平均含量为0.27%;醇溶性浸出物平均含量为18.96%.[结论] 根据抱石莲药材的显微特征能较好地将其与同属其他植物相区分.抱石莲药材中含有三萜皂苷化学成分.建议其质量标准分别控制为:水分含量≤14.00%;总灰分含量≤10.00%,酸不溶性灰分含量≤1.00%;乙醇浸提物浓度≥15.00%.%[Objective] The research aimed to study the microscopic characteristics, physical and chemical identification, contents of water, total ash, acid-insoluble ash and alcohol-soluble extracts of Lepidogrammitis drymoglossoides(Bak.) Ching and provide data for the establishment of quality standards of L. drymoglossoides. [Method] All methods were based on results of Pharmacopoeia of the People's Republic of China(2005 Edit). [Result] The histological characters of Lepidogrammitis drymoglossoides(Bak.) Ching were observed. The extract of crude drug showed positive coloration reaction with Liebermann-Burchard, Tschugaeff and Salkowski. The average content of water, total ash, acid-insoluble ash, alcoholic extract were determined as 11.98%, 7.83%, 0.27%, 18.96%, respectively. [Conclusion] Based on the microscopic characteristics of L. drymoglossoides, L. drymoglossoides could be distinguished from other plants. Alcoholic extract showed positive coloration with triterpenoid sapogenins reagent. The content of water was less than 14.00%. The content of total ash was less than 10.00%. The content of acid-insoluble ash was less than 1.00%. The content of alcoholic extract was more than 15.00%.