一种制剂中中药材原料质量控制研究

摘要

[Objective] To study the quality index of the medicinal materials in different areas and establish the quality standard of the preparation and raw materials.[Method] Various indexes of medicinal materials in different areas were determined by HPLC and method of Chinese Pharmacopoeia 2015.The content of polysaccharides in raw materials and preparations was determined by water extraction and alcohol precipitation.[Result] The content of each index of five herbs and their preparations were obtained,the quality indexes of raw materials of Chinese herbal medicines in different areas were investigated.[Conclusion] The quality standards of the Chinese herbal medicine raw materials and preparations were established.%[目的]研究不同产地药材的质量指标,建立制剂及其原料的质量标准.[方法]利用2015年版《中国药典》方法和高效液相法测定不同产地药材的各项指标,采用水提醇沉法测定原料和制剂中多糖的含量.[结果]得到了5个不同产地药材及其制剂的各种指标含量,考察了不同产地中药材原料的质量指标.[结论]建立了中药材原料和制剂产品的部分质量标准.