Objective To explore the Reason and management methods for the failed early pregnancy termination induced by medical abortion.Methods 4 020 cases of early pregnant women were involved in this study and followed up who accepted medical abortion in the out-patient department.Results Among the 4 020 medical abortion cases,490 cases failed,with a failure rate of 12.19%,in which 66 cases had non-discharged gestational sac,and 424 cases had discharged gestational sac but remaining decidual.In the decidual remaining cases,140 cases of residual area<2 cm2 underwent drug curettage,successfully in 136 cases,all the rest accepted uterine curettage.Conclusion Failed medical abortion and previous pregnancy history,gestational sac diameter,there is a close relationship between menopause and position of uterus. Medroxyprogesterone decidual residue effectively.% 目的：探讨药物流产终止早孕失败的原因及处理方法.方法：对行药物流产的4020例早孕妇女进行观察随访.结果：4020例中，药物流产失败490例，失败率为12.19%，其中妊娠囊未排出者66例，有妊娠囊排出但蜕膜残留者424例，蜕膜残留者中选140例残留面积<2 cm2的行药物性刮宫，成功者136例，其余均行清宫术.结论：药物流产失败与既往有妊娠分娩史、妊娠囊直径、停经时间和子宫位置有密切关系.安宫黄体酮治疗蜕膜残留有效.
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