Objective To investigate measures of reducing mobility of gestational diabetes mellitus( GDM)by early intervention on diet and physical activity in pregnant. Method A randomly control trial was made by starting from first trimester of pregnancy. 1083 pregnant women were divided into two groups:experimental(n=519)and control(n=564). Researchers made a face to face health education about healthy diet and physical activity during pregnancy for each subject. The experimental group were required to control their body mass and walk around for 30~60 minutes after meal twice a day. The control group did not receive the interventions mentioned above. At the end of pregnancy,the incurrence of GDM,Caesarean birth and macrosomia were calculated respectively andχ2 analysis was made. Results In the experimental group,25 pregnant women happened GDM,209 Caesarean birth,27 macrosomia. In the control group,these were 47,274,47 cases respectively. The difference between both groups was statistically significant( P﹤0. 05 ). Conclusion The combination of early diet and exercise health education intervention in pregnant women can reduce the incidence of GDM,reduce the cesarean section and macroso-mia birth.%目的：通过早期饮食和运动干预降低妊娠期糖尿病发病率。方法：采用前瞻性研究法，试验组519例，在妊娠早期（8~12周）首次产科建册检查时给予合理饮食和步行运动健康教育干预，继于孕24~26周和32~34周分别进行随访和再次干预。对照组564例未进行干预。妊娠结束后统计两组发生妊娠期糖尿病的病例数及剖宫产和巨大儿出生例数，采用χ2检验进行分析。结果：试验组发生妊娠期糖尿病25例（5.13%），对照组发生47例（8.92%），试验组妊娠期糖尿病发病率、剖宫产率和巨大儿出生率均低于对照组，差异有统计学意义（ P﹤0.05）。结论：妊娠早期孕妇接受专业的饮食和运动健康教育联合干预可以降低妊娠期糖尿病的发病率、减少剖宫产率和巨大儿出生率。
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