目的 探讨左氧氟沙星及阿奇霉素序贯疗法治疗社区获得性肺炎(CAP)的临床效果.方法 将2009年1月-2010年1月间在我院住院治疗的CAP患者56例随机分为左氧氟沙星组和阿奇霉素组,各28例;阿奇霉素组给予阿奇霉素序贯疗法,左氧氟沙星组给-予左氧氟沙星治疗.结果 左氧氟沙星组总有效率为85.71%,阿奇霉素组为82.14%,两组比较差异无显著性(P>0.05).左氧氟沙星组细菌清除率为80.00%,阿奇霉素组为76.92%,两组比较差异无显著性(P>0.05).两组患者均未见明显的药物不良反应.结论 左氧氟沙星及阿奇霉素序贯疗法治疗社区获得性肺炎疗效相当.%Objective To explore the sequential treatment effect of using levofloxacin and azithromycin to treat the patients with community acquired pneumonia. Methods The 56 cases with community acquired pneumonia in our hospital from January 2009 to January 2010 were divided into the levofloxacin group and the azithromycin group averagely; the levofloxacin group was given levofloxacin sequential treatment, and the azithromycin group was given azithromycin sequential treatment. Results The total effective rate was 85.71% in levofloxacin group and 82.14% in azithromycin group; there was no significant difference between them ( P＞0.05 ). The clearance rate was 80.00% in levofloxacin group and 76.92% in azithromycin group; there was no significant difference between them ( P＞ 0.05 ). Conclusion The levofloxacin sequential treatment and the azithromycin sequential treatment have similar effect on the treatment of community acquired pneumonia.
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