脑卒中危险度与阻塞性睡眠呼吸暂停低通气综合征相关性探讨

摘要

目的 对阻塞性睡眠呼吸暂停低通气综合症(OSAHS)与脑卒中发生的危险度的相关性进行分析.方法 将2010年3月至2013年3月间于我院就诊的45例OSAHS患者,按照呼吸暂停和低通气指数(AHI)分为低危组和高危组,患者分别为26例和19例;同时于我院住院患者中随机选择无OSAHS患者30例组成对照组.对三组患者脑卒中危险因素进行对比分析,并对OSAHS与脑卒中危险因素的相关性进行分析.结果 三组患者在年龄、吸烟指数、血压、血脂及同型半胱氨酸方面差异有统计学意义,OSAHS高危组明显高于OSAHS低危组与对照组,而OSAHS低危组则显著高于对照组,均存在统计学意义.且随着OSAHS程度的增加,年龄、吸烟指数、血压、血脂及同型半胱氨酸均明显升高.结论 脑卒中危险度与OSAHS存在显著的相关性.%Objective To analyze the correlation between obstructive sleep apnea-hypopnea syndrome (OSAHS) and the risk of stroke.Methods 45 cases of OSAHS in our hospital from March 2010to March 2013 were divided into OSAHS low-risk group (26 cases) and OSAHS high-risk group (19 cases) according to apnea and hypopnea index (AHI).At the same time randomly selected 30 patients without OSAHS in our hospital as control group.Analyzed stroke risk factors among 3 groups and the correlation between OSAHS and stroke risk factors.Results There were significant differences in age,smoking index,blood pressure,blood lipids and homocysteine among 3 groups.Age,smoking index,blood pressure,blood lipids and homocysteine in OSAHS high-risk group were significantly higher than those in OSAHS low-risk group and control group,and those in OSAHS low-risk group were significantly higher than those in control group.Age,smoking index,blood pressure,blood lipids and homocvsteine significantly went up accompanied by the increase of OSAHS degree.Conclusion It has a significant correlation between OSAHS and the risk of stroke.