米非司酮联合益母调经合剂治疗胎盘植入35例临床分析

摘要

目的 观察米非司酮联合益母调经合剂治疗胎盘植入的临床效果.方法 选取我院2000年5月至2013年5月的70例胎盘植入患者,随机均分为实验组和对照组,实验组口服米非司酮并加服益母调经合剂,对照组口服米非司酮.记录两组患者治疗前后阴道出血持续时间与出血量、胎盘排出时间、绒毛膜促性腺激素(HCG)恢复至正常的时间,比较两组临床疗效.结果 实验组患者阴道出血持续时间为(21.32±4.35)h,手术后72小时内出血总量为(349.59±72.35) ml,胎盘排出时间为(11.25±3.25) min,HCG恢复至正常的时间为(21.36±3.58)d；对照组患者阴道出血持续时间为(41.36±5.58)h,手术后72小时内出血总量为(551.25±83.28) ml,胎盘排出时间为(24.58±6.32) min,HCG恢复至正常的时间为(41.58±5.94)d.结论 米非司酮联合益母调经合剂治疗胎盘植入起效快、效果确切,值得临床推广使用.%Objective To investigate the effectiveness of mifepristone combined with leonurus emmenagogue in the treatment of placenta accreta.Methods 70 cases with placenta accreta in our hospital from May 2000 to May 2013 were randomly divided into experimental group (received oral mifepristone and leonurus emmenagogue) and control group (received oral mifepristone).The bleeding duration,bleeding amount,placenta time,recovery time of human chorionic gonadotropin (HCG) of two groups were compared.Results The bleeding durationl,bleeding amount,placenta time and the recovery time of HCG of experimental group were significantly lower than those of control group,the differences were statistically significant (p＜0.05).Conclusion Mifepristone combined with leonurus emmenagogue is an effective treatment method to placenta accreta.It has remarkable effect and fast action,which is worthy of clinical use and promotion.