高胆红素血症新生儿听力筛查的结果与临床意义探讨

摘要

Objective To explore the results and clinical significance of hearing screening in newborns with hyperbilirubinemia.Methods 160 neonates with hyperbilirubinemia who had been treated during November 2011 to November 2012 were selected for heating screening; meanwhile,200 healthy neonates were uaed as control,hyperbilirubinemia group complex screen still middel line auditory brainstem evoked potential examination was performed in those whose re-screening results were still positive.Results In hyperbilirubinemia group,the rate of abnormal evoked potential from mild to severe degree became higher and higher.The rate of abnormity was 17.5％ in the left ear rate and 22.5％ in the right ear in hyperbilirubinemia group; and it was 5.5％ in the left ear and 7.0％ in the right ear in the control group.The rates of DPOAE and ABR abnormity and the rate of recovery did not differ significantly between mild hyperbilirubinemia and moderate hyperbilirubinemia (P＞0.05) but differed significantly between severe hyperbilirubinemia and mild or moderate hyperbilirubinemia (P＜0.05).Conclusions Hyperbilirubinemia is a risk factor for dysaudia.Hearing screening for neonates with hyperbilirubinemia can reduce complications of dysaudia.%目的 探讨高胆红素血症新生儿听力筛查的结果与临床意义.方法 对2011年6月到2012年6月在我院治疗的160例高胆红素血症新生儿进行听力筛查,同时选取200例正常的新生儿作为对照,高胆红素血症组复筛后仍异常者行听觉脑干诱发电位检查.结果 高胆红素组从轻度到重度的异常比率越来越高,高胆红素组的左耳异常率为17.5％,右耳的异常率为22.5％,而正常组的左耳异常率为5.5％,右耳的异常率为7.0％；轻度和中度在DPOAE异常率、ABR异常率、恢复率比较无明显差异性,P＞ 0.05,而重度和轻、中度比较则有明显的差异性,P＜ 0.05,具有统计学意义.结论 高胆红素血症是听力障碍的危险因素,对高胆红素血症新生儿进行听力筛查可降低听力障碍并发症.