105例乳腺癌辅助内分泌治疗依从性分析

摘要

0bjective To investigate treatment compliance of adjuvant endocrine therapy in patients with breast cancer and analyze influencing factors in order to propose the solution.Methods 105 cases of breast cancer with positive ER and/or PR receptor in our hospital from January to December 2007 were selected,who all received adjuvant endocrine therapy after the surgery.Their endocrine therapy prescriptions and follow-up data were analyzed retrospectively by self-designed questionnaire.Medication possession ratio (MPR) was calculated to investigate the compliance of adjuvant endocrine therapy in patients with breast cancer.Influence factors of the compliance were explored.Results 102 cases (97.14％) were followed up successfully and divided into case group and control group according to the value of MPR.The compliance of treatment was related to cognition on the disease,outpatient review,medical environment and economic condition of patients.Conclusions The compliance of adjuvant endocrine therapy in patients with breast cancer was low.The attention should be paid to strengthening patients' health education and outpatient review,reducing financial burden of patients and increasing times of regular follow-up.%目的 了解乳腺癌辅助内分泌治疗的依从性,分析影响因素,提出对策.方法 回顾性分析2007年1月至12月在汕头市中心医院诊治的105例受体ER和(或)PR阳性的乳腺癌患者随访数据(包括门诊随访、住院随访和电话随访),运用药物占用比(MPR)及白行设计调查问卷方法,了解辅助内分泌治疗依从性及影响原因.结果 成功随访102例,占97.14％,根据MPR将102例乳腺癌患者分为依从性良好组和依从性不良组,发现疾病认知程度、复查情况、就医环境和经济状况与乳腺癌患者术后内分泌治疗依从性相关.结论 本研究乳腺癌患者辅助内分泌治疗总体依从性偏低.可从加强患者健康教育、定期门诊复查、减轻患者经济负担、定期随访四方面来提高内分泌治疗依从性.