Objective To discuss the clinical features of neonatal shock retrospectively.Methods Totally 144 neonates were enrolled in this retrospective study from Sep.2006 to Sep.2012 in NICU of Beijing Children's Hospital.Clinical data were collected from our database,including the primary disease,manifestation,laboratory findings,treatment and prognosis.Results According to the severity of shock,28 cases were mild,85 were moderate,31 were severe.Regarding to the type of shock,71 cases were cardiogenic shock,22 cases were hypovolemic shock,51 cases were septic shock.About 69.4% patients were cured,only 9 cases died.Eight of them died of septic shock.Totally 33 cases in pH <7.15 group,2 of them died.In pH≥7.15 group,111 cases were involved,7 of them died.There was no significant difference of mortality between two groups (P =0.959).Conclusion Neonatal shock mostly occurred within 3 days after birth,and cardiogenic shock were dominating.Septic shock increased with age,and were responsible for death.%目的 探讨新生儿休克的临床特点.方法 收集2006年9月至2012年9月收治于我院新生儿重症监护病房144例诊断新生儿休克患儿资料,总结其原发病、临床表现、实验室检查、治疗和预后.结果 144例新生儿休克中轻度28例,中度85例,重度31例.心源性休克71例,低血容量性休克22例,感染性休克51例.治愈100例(69.4%),未愈35例(24.3%),死亡9例(6.3%),死于感染性休克8例.动脉血气pH<7.15者33例,死亡2例;pH≥7.15者111例,死亡7例,两组病死率差异无统计学意义(P =0.959).结论 新生儿休克多发生在生后3d内,以心源性休克最多见,随着日龄的增加,感染性休克增多,并成为新生儿休克的主要死亡原因.
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