Prader-Willi 综合征和睡眠相关呼吸紊乱的关系

摘要

Prader-Willi syndrome( PWS) is a type of genetic disease,which is associated with low mus-cle tone,growth and development,progressive fatal obesity and sleep related respiratory disorders(SRBD). Ob-structive sleep apnea hypopnea syndrome( OSAHS) is the most common type of SRBD. The cause,influencing factors and treatment of OSAHS in patients with PWS are described in this paper. To understand the degree of OSAHS in children with PWS,the polysomnography is recommended.%Prader-Willi综合征是一种基因遗传疾病，该病多伴有肌张力低下、生长发育迟缓、进行性致死性肥胖和睡眠相关呼吸紊乱等。阻塞性睡眠呼吸暂停低通气综合征是睡眠相关呼吸紊乱最常见类型。该文从Prader-Willi综合征存在睡眠相关呼吸紊乱特别是阻塞性睡眠呼吸暂停低通气综合征的发病原因、影响因素及治疗方案进行阐述，并建议对Prader-Willi综合征患儿进行多导睡眠监测以了解该患儿的阻塞性睡眠呼吸暂停低通气综合征程度。