川崎病冠状动脉损伤机制及治疗新进展

摘要

Kawasaki disease,also known as multiple mucocutaneous lymph node syndrome,is a self-limiting and acute systemic vasculitis.Kawasaki disease is often complicated by coronary artery lesions.Kawasa-ki disease is a leading cause of coronary artery lesions in childhood in developed countries.The mechanisms of coronary artery lesions and new therapeutic regimens have been the hotpots in research of Kawasaki disease.This paper reviews current research on mechanism of coronary artery lesions and development of new therapeutic regi-mens.%川崎病也称为皮肤黏膜淋巴结综合征，是一种具有自限性、由免疫介导的全身中小血管的炎性综合征，其中冠状动脉最易受累。目前川崎病已逐渐成为发达国家儿童冠状动脉损伤的首位病因。冠状动脉的损伤机制及治疗是目前川崎病研究的热点。该文就川崎病引起冠状动脉损伤的机制及治疗最新进展作一综述。