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2861例妊娠期妇女TORCH筛查结果回顾性分析

     

摘要

Objective To study TORCH screening results of pregnant woman in different season and age. Methods TORCHIgM and IgG in 2 861 cases of serum samples from pregnant women were detected by chemiluminescent, including Toxoplasma gon-dii(TOX) ,Rubella(RUB) ,Cytomegalovirus(CMV) and Herpes simplex virus(HSV). Results The positive rate of HSV IgM was 22. 13% and was the highest among TORCH IgM. The positive rate of HSV1/2 IgG was 3. 64% and was the highest among TORCH IgG. The positive rate of HSV-IgM(52. 96%) in >40 - 45 age group was significantly higher than other four age groups (P<0. 05). In summer,the positive rate of TOX IgM was 1. 68% ,higher than in spring and winter(P<0. 05). It was 0. 75% in autumn,higher than in winter(P<0. 05). There was no statistical difference of the positive rate of TOX IgM between winter and spring(P>0. 0). Conclusion The positive of TORCH IgM and IgG could separately clue to the different diagnostic means and it could be great significant to promote birth quality and improve population quality. This conclusion could provide a valid reference for choice of pregnant.%目的 研究不同季节、不同年龄段妊娠期妇女TORCH抗体阳性率.方法 采用化学发光免疫分析法对2 861例孕妇进行血清TORCH IgM、IgG抗体筛查,包括弓形体(TOX)、风疹病毒(RUB)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV).结果 TORCH IgM筛查中,HSV IgM阳性率最高,为22.13%;TORCH IgG筛查中,HSV1/2 IgG阳性率最高,为3.64%;>40~45岁年龄段HSV IgM阳性率为52.96%,高于其他年龄段(P<0.05);夏季TOX IgM阳性率为1.68%,高于冬、春季(P<0.05),秋季为0.75%,高于冬季(P<0.05),冬、春两季间差异无统计学意义(P>0.05).结论 TORCH IgM及IgG阳性分别代表急性或既往感染,对于临床开展优生优育筛查具有非常重要的意义.本次调查为本地区妇女选择合适的年龄和季节怀孕提供了参考.

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