邯郸地区黄疸婴儿人类巨细胞病毒感染的调查分析

摘要

Objective To investigate the status of human cytomegalovirus(HCMV) infection in infants with jaundice,and to e-valuate the statistical difference between the positive rate of HCMV-DNA and sexes. Methods FQ-PCR was used to detect HC-MV-DNA in urine from 190 infants with jaundice. Results Among the 190 cases 96 were positves(53. 2%). The positive rate of HCMV-DNA in boys was 59. 6% ,and 39. 5 in girls,the difference between boys and girls was statistically significant(P<0. 05). Conclusion HCMV is one of the most important factions resulting in infants with jaundice of Handan. There is statistical difference between sexs.%目的 调查邯郸地区黄疸婴儿人类巨细胞病毒(HCMV)感染的情况,探讨HCMV-DNA感染率是否与性别相关.方法 采用荧光定量PCR方法对190例黄疸婴儿尿液标本进行HCMV-DNA定量检测.结果 在所检测的190例黄疸婴儿中,婴儿尿液HCMV-DNA阳性有96例,感染率为53.2％,其中男婴的阳性率为59.6％,女婴的阳性率为39.5％,阳性率在性别间分布差别有统计学意义(P＜0.05).结论 HCMV是邯郸地区引起婴儿黄疸的最主要原因之一,且HCMV感染率与性别相关.