12757例公共场所从业人员梅毒检测结果分析

摘要

Objective To understand the infection situation of syphilis among the employees in public places in Nanning city and its epidemiological features.Methods 12 757 hematological specimens from the employees in public places in Nanning city were collected.The toluidine red unheated serum test(TRUST)was adopted for screening syphilis and the syphilis infectors confirmed by the positive result in treponema pallidum particle agglutination assay(TPPA)were analyzed.Results Among 12 757 research subjects,253 cases were confirmed the syphilis positive with the positive rate of 1.98%.By means of the χ2-test for the comparison among groups,4 319 cases were males with the positive the rate of 2.92%,while 8 438 cases were females with the positive the rate of 1.51%,the difference between them was statistical significance(χ2 =29.925,P <0.01);the research subjects were divided into 4 age groups,in the age 7-29 years,9 209 cases were positive with the positive rate of 0.90%;the age 30-<40 years,2480 cases were positive with the positive rate of 4.84%;the age 40-<50 years,890 cases were positive with the positive rate of 5.17%;the age 50-<70 years,178 cases were positive with the positive rate of 2.25%,the differences among the various age groups had sta-tistical significance(χ2 =205.9966,P <0.01).The age 40-<50 years group had the highest syphilis positive rate,followed by the age 30-<40 years group,and the age 17-29 years group had the lowest syphilis positive rate.Conclusion The persons aged 30-49 years are the highest risk population of syphilis infection.The comprehensive measures should be taken to prevent the syphilis infection and transmission.%目的：了解南宁市公共场所从业人员梅毒感染情况及流行病学特征。方法收集南宁市公共场所从业人员12757例血液学样本，采用甲苯胺红不加热试验（TRUST）筛查梅毒，以梅毒螺旋体明胶凝集试验（TPPA）阳性确认梅毒感染人数的情况进行分析。结果12757研究对象的梅毒阳性人数253人，阳性率1．98％。用χ2检验进行组间的比较。其中男性4319人，阳性率2．92％，女性8438人，阳性率1．51％，梅毒感染阳性率在性别上有差异，具有统计学意义（χ2＝29．925，P ＜0．01）；分4个年龄段进行比较，17～＜30岁有9209人，阳性率0．90％；30～＜40岁有2480人，阳性率4．84％；40～＜50岁有890人，阳性率5．17％；50～＜70岁有178人，阳性率2．25％。各个年龄组间阳性率比较，差异具有统计学意义（χ2＝205．996，P ＜0．01）。梅毒阳性率在40～49岁年龄段最高，30～39岁年龄段次之，17～29岁年龄段最低。结论40～49岁已成为梅毒感染的高危人群，应采取综合措施防控梅毒感染和传播。