目的：探讨不同方法联合检测在孕妇 TORCH感染中的应用价值。方法采用酶联免疫吸附法对孕妇进行血清TORCH特异性IgM抗体进行检测，孕妇每两周接受1次超声检查，观察胎儿发育情况。结果656例孕妇中，TORCH感染率为19．36％。其中弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒特异性Ig M 抗体阳性率分别为3．50％、2．13％、4．27％、4．72％。T O RC H特异性抗体阳性者超声检查检出的胎儿发育异常包括脐膨出37例、颈部淋巴水囊肿12例、停止发育4例、脑积水6例、死胎9例、单脐动脉肾盂积水16例、腹裂12例、发育迟缓24例，总异常率为18．29％。656例妊娠妇女中，正常分娩574例，其中T O RC H感染者56例，占9．76％；妊娠结局不良82例，其中T O RC H感染43例，占52．44％，与正常分娩者中T O RC H感染者所占比例比较差异有统计学意义（P＜0．05）。结论超声与血清学检测联合应用于孕妇TORCH感染诊断，方法可靠，能够有效地提高人口素质。%Objective To study the use of ultrasound and serological diagnosis of TORCH infection in pregnant women .Methods Enzyme linked immunosorbent assay of serum IgM antibodies specific for TORCH were performed .Biweekly ultrasonic inspec‐tion were also performed to detect fetal development .Results Among 656 cases of pregnant women ,the TORCH infection rate was 19 .36% ,and the positive rates of IgM specific for toxoplasma ,Rubella virus ,cytomegalovirus ,herpes simplex virus were 3 .50% , 2 .13% ,4 .27% and 4 .72% .Among TORCH antibody positive pregnant women ,ultrasound abnormality included 37 cases of omphalocele ,12 cases of cervical lymph hydrocyst ,4 cases of growth‐stopping ,6 cases of hydrocephalus ,9 cases of fetal death ,16 cases of single umbilical artery hydronephrosis ,12 cases of gastroschisis ,24 cases of intrauterine fetal growth retardation ,and the total abnormal rate was 18 .29% .Among 656 cases of pregnant women ,there are 574 cases of normal deliveries ,including 56 cases of TORCH infection ,accounting for 9 .76% ,and 82 cases with adverse pregnancy outcome ,including 43 cases of TORCH infection , accounting for 52 .44% ,which was higher than that in pregnant women with normal deliveries(P<0 .05) .Conclusion Ultrasound and serological diagnosis of TORCH infection could be reliable and effectively improve the quality of the population .
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