目的：评估结核感染T细胞检测在菌阴性肺结核的诊断价值。方法纳入包括菌阴性肺结核病患者145例、非结核肺部疾病患者45例共190例。所有研究对象进行结核感染T细胞检测，计算灵敏度、特异度、阳性预测值、阴性预测值等指标。结果结核感染T细胞检测对菌阴性肺结核诊断的灵敏度为85．5％，特异度为84．4％，阳性预测值为94．7％，阴性预测值为64．4％。不同年龄段间比较差异无统计学意义（ P＞0．05）。结论结核感染 T细胞检测有较高的阳性预测值，适用于菌阴性肺结核病的临床辅助诊断。%Objective To evaluate the application value of T cell infected with Mybacterium tuberculosis assay in diagnosis of smear and culture negative pulmonary tuberculosis .Methods In total ,145 patients with smear and culture negative pulmonary tu‐berculosis and 45 patients with non‐tuberculosis lung disease were enrolled in the study .All patients received T cell infected with Mybacterium tuberculosis test and sensitivity ,specificity ,positive predicted value ,negative predicted value of testing for the diagno‐sis of smear and culture‐negative TB patients were calculated .Results The sensitivity of specificity T cell infected with Mybacteri‐um tuberculosis assay in diagnosis of smear and culture negative pulmonary tuberculosis was 85 .5% ,the specificity was 84 .4% , positive predicted value was 94 .7% ,negative predicted value was 64 .4% .No statistical significance in age‐dependent groups(P>0 .05) .Conclusion T cell infected with Mybacterium tuberculosis assay has high positive predicted value in diagnosis of smear and culture negative pulmonary tuberculosis and is suitable for clinical auxiliary diagnosis .
展开▼
