IgG抗-E合并IgG＋IgM抗-Mur致交叉配血不合分析

摘要

目的：对输血前检测中发现抗‐E 、抗‐Mur 的患者进行血型血清学特异性鉴定，分析其在输血中的临床意义。方法采用微柱凝胶法检测患者血清与抗体筛查谱细胞的反应格局，鉴定抗体的种类及特异性。结果2例患者血清中均存在 IgG 抗‐E 合并 IgG ＋ IgM 抗‐Mur 3种抗体。结论抗‐E 与抗‐Mur 都易引起溶血性输血反应，准确的抗体鉴定基础上挑选合适的供血者，可为输血安全提供保障。%Objective To perform the serological identification of anti‐E and anti‐Mur found in the detection before blood trans‐fusion and to analyze its clinical significance in blood transfusion .Methods The reaction pattern of serum with the antibody screen‐ing spectrum was detected by using the micro‐column gel method for identifying the antibody type and specificity .Results The 3 kinds of antibody anti‐E IgG combined with anti‐Mur IgG + IgM existed in the serum of 2 patients .Conclusion Anti‐E and anti‐Mur all are easier to lead to the hemolytic blood transfusion reaction .Selecting the suitable donor on the basis of the accurate anti‐body identification can provide guarantee for blood transfusion safety .