难治性青光眼治疗进展

摘要

难治性青光眼病因复杂，多种发病机制并存，药物治疗不理想，常规滤过性手术成功率低。手术失败主要原因是滤过口处成纤维细胞增殖以及瘢痕形成使滤过口阻塞。手术治疗方法众多，联合的小梁切除术、青光眼引流物植入术、睫状体光凝术等是难治性青光眼常用的手术方式，而青光眼引流物植入术是目前公认的难治性青光眼的首选手术方式。本文对难治性青光眼的常用手术方式的临床疗效及术后并发症等进行综述。%Refractory Glaucoma is a kind of intractable eye disease with strong destruction and high blindness rate, the failure rate of which is very high. The mainly reason is fibroblasts hyperplasia and scarring on filtration mouth that hindered the drainage and diffusion of aqueous. Combined trabeculectomy, glaucoma drainage device implantation, and cyclophotocoagulation are the common surgical procedures for refractory glaucoma. So far, glaucoma drainage device implantation is regarded as the first-line choice. The authors focus on the clinical efficacy and prospect of the surgery way for refractory glaucoma.