AIM: To evaIuate the difference of ocuIar surface between Resight non - contact wide - angIe Iens and conventionaI corneaI contact Iens in the patients with proIiferative diabetic retinopathy ( PDR ) after phacoemuIsification combined with intraocuIar Iens( IOL) impIantation and vitrectomy. METHODS:A retrospective cases-controIIed study was designed. Ninety-six patients ( 96 eyes ) with PDR and cataract were incIuded in this study from January 2014 to December 2014 in TraditionaI Chinese MedicaI HospitaI of Xinjiang Uygur Autonomous Region. The 48 cases ( 48 eyes) in experiment group were treated with Resight non-contact wide-angIe Iens,the 48 cases(48 eyes) in controI group with conventionaI corneaI contact Iens. CorneaI thickness(CT), Schirmer’s test(SIt),breaking-up time ( BUT) and corneaI fIuorescein staining( CFS) were taken before operations and at 1d, 1wk and 1mo after operations. RESULTS: AII indicators of the two groups had no significant differences preoperativeIy. Significant differences were found on CT vaIue between the experiment group and controI group as weII as among 4 time points ( Ftime=748. 355, P=0. 000;Fgroup =27. 196, P=0. 000 ) . The CT vaIue of the controI group increased obviousIy after surgeries, the differences were significant compared with preoperative (P<0. 05). The SIt of the two groups among the 4 points were significantIy different (Ftime=571. 094,P=0. 000). The SIt of the two groups at 1d and 1wk were significantIy different compared with those preoperative(P<0. 05). The SIt of the two groups at 1mo postoperativeIy recovered to the same IeveI as before surgeries. The BUT vaIue between the two groups as weII as among 4 time points were significantIy different (Ftime=843. 122,P=0. 000;Fgroup=24. 664,P=0. 000). The BUT decreased after surgeries and the differences were significant, compared with those before surgeries ( P<0. 05 ) . The CFS vaIue between the two groups as weII as among 4 time points were significantIy different(Ftime=312. 093,P=0. 000;Fgroup=16. 232,P=0. 000). The CFS vaIue after surgeries was higher than those before surgeries and the differences were significant (P<0. 05). CONCLUSION: Resight non-contact wide-angIe Iens has IittIe infIuence on the ocuIar surface in the patients with PDR after phacoemuIsification combined with IOL impIantation and vitrectomy.%目的：探讨Resight非接触式广角镜与传统角膜接触镜在增生性糖尿病视网膜病变( proliferative diabetic retinopathy,PDR)患者眼前后节联合手术后眼表的差异性比较。方法：回顾性分析2014-01/12在新疆自治区中医院眼科住院收治的白内障合并增生性糖尿病视网膜病变的患者96例96眼,其中采用白内障超声乳化摘除+人工晶状体植入联合23 G玻璃体切割术辅助Resight非接触式广角镜48例48眼设为试验组,对照组48例48眼为采用传统角膜接触镜,余均同对照组。两组患者性别及年龄、病程均匹配。观察术前、术后第1、7、30 d的角膜厚度( corneal thickness,CT)、基础泪液分泌量( Schirmer’s test,SⅠt)、泪膜破裂时间( breaking-up time, BUT )、角膜荧光染色( corneal fluorescein staining,CFS)。结果：两组患者术前各项指标均无统计学差异,两个组手术前后各时间点的 CT 值总体比较差异有统计学意义(F时间=748.355,P=0.000；F组别=27.196,P=0.000),其中对照组术后各时间点角膜厚度均明显增加,与术前相比,差异均有统计学意义(P<0.05)；两个组手术前后不同时间点 SⅠt 值总体比较差异有统计学意义(F时间=571.094,P=0.000),其中两组术后1、7d S I t值与术前相比差异均有统计学意义(P<0.05),术后30d S I t值均逐渐恢复至术前水平；两个组手术前后不同时间点的BUT值总体比较差异有统计学意义( F时间=843.122,P=0.000；F组别=24.664,P=0.000),其中对照组术后各时间点BUT值均缩短,与术前比较差异有统计学意义( P<0.05),两个组术眼CFS值不同组间和不同时间点的变化差异均有统计学意义( F时间=312.093, P=0.000；F组别=16.232,P=0.000),其中,两个组患者术后各时间点的CFS值均高于术前,差异均有统计学意义( P<0.05)。结论：Resight非接触式广角镜在PDR患者眼前后节联合手术后对眼表影响小,术后干眼症状较轻。
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