脉络膜厚度与体温日间变化的研究

摘要

AIM: To investigate how body temperature (BT) affects choroidal thickness (CT) according to measurements taken with enhanced depth imaging optical coherence tomography (EDI-OCT).METHODS: In this prospective study, the CT of 41 healthy patients was measured hourly from 9∶00 to 17∶00 at the fovea (SF-CT), 500 μm nasal to the fovea(N-CT), and 500 μm temporal to the fovea (T-CT) using EDI-OCT.BT was also measured hourly from 9∶00 to 17∶00 using a non-contact infrared thermometer.Possible correlations between diurnal variations of CT and BT were evaluated.RESULTS: SF-CT values significantly differed between measurements at 9∶00 and 13∶00 (P=0.021), 9∶00 and 14∶00 (P=0.012), 9∶00 and 16∶00 (P=0.048), and 9∶00 and 17∶00 (P=0.002).N-CT values also significantly differed between measurements at 9∶00 and 13∶00 (P=0.004), though T-CT did not significantly vary during the 8h period (P >0.05 for all).CONCLUSION: CT is not significantly associated with hourly changes in BT from 9∶00 to 17∶00.%目的:通过深度增强成像光断层扫描(EDI-OCT)技术以探究体温如何影响脉络膜厚度.方法:前瞻性研究.通过EDI-OCT检测9∶00~17∶00中心凹(SF-CT),中心凹鼻侧500μm(N-CT)和中心凹颞侧500μm(T-CT)正常人(41例)的脉络膜厚度(CT).使用非接触式红外测温仪逐时检测体温(BT),以评估CT和BT日间变化的相关性.结果:SF-CT值在9∶00和13∶00(P=0.021),9∶00和14∶00(P=0.012), 9∶00和16∶00(P=0.048),及9∶00和17∶00(P=0.002)之间存在显著性差异.N-CT值在8h内(均P>0.05)无显著性变化,9∶00和13∶00(P=0.004)则存在明显差异.结论: CT与BT从9∶00~17∶00之间逐时变化无显著性差异.