AIM:To investigate the clinical effect of pills of six ingredients with rehmannia combined with ginkgo biloba leaf table in the prevention and treatment of early retinopathy in patients with type 2 diabetes mellitus.METHODS:A total of 82 patients (82 eyes) with type 2 diabetes mellitus who were treated with endoscopy from January 2013 to January 2015 were randomly divided into observation group and control group according to the random number table method.The control group was given conventional western medicine treatment, the observation group in the control group was given pills of six ingredients with rehmannia combined with ginkgo leaf table treatment besides the control group treatment.The diabetic retinopathy was assessed in both groups, as well as changes in blood glucose, blood pressure, and glycosylated hemoglobin.We recorded the occurrence of adverse reactions during and after treatment.RESULTS: The new diagnosed rate and the progress rate of observation group were lower than those of the control group, remission rate was higher, and the difference was statistically significant (P0.05).The incidence of adverse reactions between the two groups was not statistically significant (P>0.05).CONCLUSION: Type 2 diabetes mellitus patients treated with pills of six ingredients with rehmannia combined with ginkgo biloba leaf table can effectively control the rate of retinopathy, the rate of progress, improve the rate of remission with high drug safety, and have the significance of further clinical research.%目的:探讨六味地黄丸联合银杏叶片防治2型糖尿病早期视网膜病变的临床效果.方法:选取2013-01/2015-01于我院内分泌科门诊进行治疗的2型糖尿病患者82例82眼,依据随机数字表法随机分为观察组和对照组,每组41例41眼.对照组给予常规西医治疗,观察组在对照组治疗的基础上给予六味地黄丸联合银杏叶片治疗.评估两组患者糖尿病视网膜病变情况,以及血糖、血压以及糖化血红蛋白指标变化.记录治疗期间以及治疗后两组不良反应的发生情况.结果:本次研究显示:观察组患者糖尿病视网膜病变新增率以及进展率均低于对照组,缓解率高于对照组,组间差异有统计学意义(P0.05).两组患者不良反应发生率差异无统计学意义(P>0.05).结论:六味地黄丸联合银杏叶片可以有效控制2型糖尿病早期视网膜病变新增率、进展率,提高缓解率,药物安全性高,具有进一步临床研究的意义.
展开▼
