门脉高压是各种原因所致肝内血管阻力增大和门静脉血流量增加的结果,是肝硬化严重并发症(静脉曲张出血和顽固性腹水)的主要死亡原因,特别是在失代偿期肝硬化患者中,进行门脉高压早期评估、治疗及管理能够有效降低严重并发症发生率和患者病死率.目前测量肝静脉压力梯度是公认的评估门脉高压程度的金标准,近年来无创诊断评估手段层出不穷,但能够应用于临床的技术较少;针对门脉高压的治疗包括药物治疗、内镜治疗、微创介入、外科手术和肝移植等.本文就目前门脉高压的诊断及治疗新进展作一综述.%Portal hypertension is the consequence of increasing intrahepatic vascular resistance and increasing portal venous blood flow due to various causesis caused by various reasons intrahepatic vascular resistance increased and portal venous blood flow increase as a result, and is the main leading cause of death in cirrhosis severe complications (varices bleeding and refractory ascites), especially in patients with decompensated cirrhosis, early evaluation and treatment management of portal hypertension can effectively reduce the incidence of severe complications and mortality. At present, the measurement of hepatic venous pressure gradient is well recognized as the gold standard for the evaluation of portal hypertension severity. Non-invasive diagnostic assessments have frequently emerged within recent years, but few technology is available for clinical application. Clinical treatment of portal hypertension includes drug therapy, endoscopic therapy, minimally invasive intervention, surgical operation and liver transplantation. This study aims to review new advance in diagnosis and treatment of portal hypertension.
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