目的 研究肾衰康口服液对氢化可的松致小鼠肾阳虚动物模型的影响.方法 制备氢化可的松致小鼠肾阳虚模型;肾衰康口服液(30.0,15.0,7.5 g·kg-1)灌胃给药,qd,连续10d,观察肾衰康口服液对肾阳虚小鼠体质量,体温,免疫器官(胸腺、脾、肾上腺)和性器官(包皮腺、睾丸、前列腺)的影响.结果 肾衰康口服液30 g·kg-1给药组可使模型小鼠的体质量、体温明显恢复,并可明显增加小鼠胸腺、脾、肾上腺、包皮腺、睾丸和前列腺指数.结论 肾衰康口服 液对氢化可的松所致小鼠肾阳虚症状有显著的改善作用.%Objective To study the effects of shenshuaikang oral liquid on kidney-yang deficiency mite induced byrnhydrocortisone. Methods , The kidney-yang deficiency model was induced by I. P. Hydrocortisone in mice. Shenshuaikang oral liquid(30.0,15. 0,7. 5 g · kg"1 ) was oralls administered once a day fur 10 days. Effects of shenshuaikang oral liquid were detected on the body mass, body temperature, immune, organs (thymus,spleen, adrenal gland ), and genitals (foreskin gland, testis,prostate) in kidney-yang deficiency mice. Results The results showed that body weight, body temperature were improved significantly by shenshuaikang oral liquid at the dose of 30.0 g·kg-1 and the index of thymus,spleen,adrenal gland, prostate,testis and preputial gland were significantly increased. Conclusion Shenshuaikang oral liquid can significantly ameliorate kidney-yang deficiency induced by hydrocortisone in mice.
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