金柴抗感胶囊解热抗炎止咳作用研究

摘要

Objective To investigate the antipyretic, anti-inflammatory and antitussive effects of jinchai kanggan capsules. Methods The antipyretic, anti-inflammatory and antitussive activities of the preparation were observed in the yeast induced fever in rats, croton oil induced auricular edema in mice, and aqua ammoniae induced cough in mice, respectively. Results The jinchai kanggan capsules reduced body temperature elevation in rats between 3 ～ 6 h, alleviated auricular edema and prolonged cough incubation in mice. Conclusion The jinchai kanggan capsule has antipyretic, anti-inflammatory, and antitussive effects.%目的 观察金柴抗感胶囊的解热抗炎止咳作用.方法 通过大鼠干酵母致发热模型观察金柴抗感胶囊解热作用；通过小鼠巴豆油致耳廓肿胀模型观察金柴抗感胶囊抗炎作用；通过小鼠氨水引咳模型观察金柴抗感胶囊止咳作用.结果 金柴抗感胶囊能显著降低大鼠第3～6小时体温升高值；减轻小鼠耳廓肿胀度；延长小鼠咳嗽潜伏期.结论 金柴抗感胶囊具有解热抗炎止咳作用.