肺动脉高压及肺血管重构的研究进展

摘要

肺动脉高压（PAH）表现为以肺血管重构为主要病理变化的特征性疾病，是一种复杂性、渐变性病变，最终可能导致右心衰竭。肺血管重塑机制复杂，涉及血管各细胞层的病理性变化，对细胞水平的全面了解有重要意义。本文就当前的研究进展做一综述。%pulmonary arterial hypertension(PAH)is a characteristic disease showed the main pathological changes of pulmonary vascular remodeling,which is a complex and gradual disease that could lead to right heart failure eventually.Pulmonary vascular re-modeling has complex mechanisms which involvs vascular pathological changes of each cell layer.Having a comprehensive under-standing of the cellular level is significantt. In this paper, the current research progress is reviewed.