Objective To investigate the influence on the lung resection patients restlessness and hemodynamics after general anesthe -sia when they transfused dexmedetomidine .Methods Elective 42 patients that took lung resection at our hospital from January 2014 to Oc-tober as cases.All of they belonged to ASAⅠ~Ⅱgrade, which were completely randomly divided into the observation group and the control group, 21 cases each.Two groups of patients were treated with conventional anesthesia , off his chest in the observation group dexmedetomi-dine infusion set, infusion of normal saline control group , compared two groups in the agitation score and blood pressure and heart rate .Re-sults Two groups in blood pressure and heart rate had no statistically significant difference at preoperative (P>0.05).After extubation 1, 5,10mins, observation group′s blood pressure, heart rate was significantly lower than the control group (P<0.05), the observation group′s postoperative hypertension and EA incidencewas were significantly lower than the control group (P<0.05).Conclusion Given dexme-detomidine could significantly reduce the incidence of lung cancer patients undergoing radical EA, and could effectively stabilize blood pres-sure and heart rate of patients after general anesthesia , which was worthy of clinical use .%目的：探讨在肺癌根治术中输注右美托咪定对患者全麻苏醒期躁动（ EA）及血流动力学的影响。方法选取2014－01～2014－10间于罗定市人民医院择期进行肺癌根治术的42例ASA分级Ⅰ～Ⅱ级患者，将其随机分为观察组及对照组，每组各21例。两组患者均采用常规麻醉方式，关胸前观察组静脉输注右美托咪定，对照组输注等量生理盐水，对比两组患者躁动评分及术后不同时刻血压及心率。结果术前两组患者血压及心率比较无统计学差异（P＞0．05），拔管后T 1、T 2、T 3血压、心率比较观察组显著小于对照组（ P＜0．05），术后观察组高血压、EA发生率均显著低于对照组（ P＜0．05）。结论右美托咪定可明显降低肺癌根治术患者EA的发生率，并能有效稳定术后患者的血压及心率，值得临床推广使用。
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