鲑鱼降钙素和唑来膦酸治疗绝经后骨质疏松症的成本－效果分析

摘要

Objective To study the cost-effectiveness of calcitonin salmon and zoledronic acid in treating postmenopausal osteoporo-sis.Methods 126casesofpostmenopausalosteoporosiswerecollectedandrandomlydividedintotwogroups:groupAandgroupB.Data was evaluated using the cost-effectiveness analysis of pharmacoeconomics.Results The costs of group A and group B were 2 279.42 and 3 316.79 yuan respectively.The total effective rates of group A and group B were 57.14%and 79.37%respectively.Group B was higher than those in group A,and the difference was statistically significant in two groups (P<0.05).The cost-effectiveness ratios (C/E) of group A and group B were 39.89 and 41.78 respectively.Conclusion Group B has better compliance and is more reasonable as compared with group A.%目的：比较鲑鱼降钙素和唑来膦酸治疗绝经后骨质疏松症（ PMOP）的成本与效果。方法将126例PMOP患者分为A组和B组，运用药物经济学原理进行成本－效果分析。结果 A组和B组的治疗成本分别为2279．43元和3316．79元；总有效率分别为57．14％和79．37％，B组明显高于A组，有统计学差异（ P＜0．05）；经济学方面A组和B组的成本－效果比分别是39．89和41．79。结论应用唑来膦酸治疗绝经后骨质疏松症比鲑鱼降钙素更为合理。