慢性肺源性心脏病患者急性期血清CKP、LDH和AST测定及临床意义

摘要

目的：探讨慢性肺源性心脏病（简称肺心病）患者急性期血清磷酸肌酸激酶（CPK）、乳酸脱氢酶（LDH）和天门冬酸氨基转移酶（AST）的变化。方法：检测20例正常对照组、33例急性发作期和20例缓解期肺心病患者血清CPK、LDH和AST，并同时作血气分析。结果：肺心病患者血清CPK、LDH和AST明显高于正常对照组，且急性期高于缓解期（P＜0.01）；血清CPK、LDH和AST与PaO2呈负相关，与PaCO2呈正相关。结论：血清CKP、LDH和AST测定可反映肺心病病情。%Objective：To study the change of serum creatine phosphokinase （CPK） lactate dehydrogenase （LDH） and aspartic transaminase （AST） in chronic cor pulmonale patients acute peroid．Methods：Serum CPK，LDH and AST were determined in 20cases normal control，33 cases acute attacking peroid and 20 cases remission peroid cor pulmonale patients；at the same time blood gas analysis were made．Results：Serum CPK，LDH and AST in cor pulmonale patients were marked higher than these in normal control group，and these of acute peroid were higher thanremission peroid；serum CPK，LDH and AST were negative correlation with partial pressure of oxygen （PaO2），and positive correlation with partial pressure of carbon dioxide （PaCO2）．Conclusion：Determining serum CKP，LDH and AST can reflect cor pulmonale patientss condition．