合并心脏损害的儿童过敏性紫癜临床分析

摘要

目的:探讨儿童过敏性紫癜(HsP)合并心血管损害的临床特点、发生机制和预后.方法:对临床明确诊断的280例儿童HSP患儿进行回顾性分析.结果:280例儿童过敏性紫癜患儿中有87例并发心脏损害,占31.1%,其中表现为心电图异常51例,占18.2%,和(或)有心肌酶谱改变69例,占24.6%,混合性紫癜患儿心电图、心肌酶谱异常率高,异常程度也较重,心损脏损害组与无心脏损害组相比,多脏器损害比例明显增高,治疗后心电图、心肌酶谱有不同程度的恢复.结论:临床上应将心肌酶谱、心电图检测作为HSP的常规检查,有异常者及早进行干预,使可逆性的心肌损害得到恢复,对患儿顸后具有重要临床意义.%Objective: To study the clinical characteristics, pathogenesis and prognosis of children with henoch-schonlein purpura (HSP). Method: The data of 280 children diagnosed with HSP were reviewed retrospectively. Result: Among the 280 cases, 87 ( 31.1% ) were combined with cardiac damage . 51 (18.2%) were combined with ECG abnormalities . 69 ( 24.6% ) were combined with the changing of myocardial enzymes. The abnormal rate of children with mixed purpura is high and the abnormal level is also high .Compare with the team without cardiac damage , the rate of multiple organ damage of the team with cardiac damage is higher. After treatment, the ECG and myocardial enzymes are restored in a extent. Conclusion:We should take the ECG and myocardial enzymes as a routine inspection of HSP clinically. Early intervention is contribute to the damaged myocardial to recover, which have a clinical significance in prognosis.