红细胞分布宽度与慢性心力衰竭预后的关系

摘要

目的:分析红细胞分布宽度(RDW)与慢性心力衰竭(CHF)预后的关系,并探讨RDW作为CHF标志物的可能性.方法:收集近2年来入院心衰患者共200例的资料,根据纽约心功能分级分为心功能Ⅱ级组(n=66)、Ⅲ级组(n=58)、Ⅳ级组(n=76);另选182例同期住院无慢性心力衰竭的患者作为对照组.将慢性心力衰竭患者分为两组:RDW增高组(n=102),RDW正常组(n=98),比较二者的死亡率.结果:从对照组到心功能Ⅳ级组,RDW逐渐增加,各组间两两比较差异均具有统计学意义(P＜0.01);RDW增高组CHF患者死亡率较RDW正常组明显升高(P＜0.05).结论:CHF患者RDW明显升高,且与心衰程度有关;心衰患者入院时RDW水平与慢性心力衰竭不良事件的发生存在明显相关性.%Objective: To study the relationship between red blood cell volume distribution width ( RDW )with the chronic heart failure(CHF ), to explore the possibility as a laboratory markers of risk. Method: 200 cases of patients with chronic heart failure in hospital were collected and divided into three groups by NYHA: class Ⅱ( n = 66 ), classⅢ( n = 58 ), class M n = 76 );182 patients without CHF were selected as the control group. 200 patients with chronic heart failure were divided into two groups, group A : RDW is normal( n = 98 ); group B:RDW is above normal( n = 102 ), compare their mortality. Result: There were significant differences about RDW among the four groups( P<0.01 ); The mortality was higher in group B than that in group A( P<0. 05 ). Conclusion: RDW in CHF patients is significantly higher than in the control group without CHF, and it correlates with the degree of heart failure; the level of RDW in CHF patients is obviously related with the prognosis.