picco指导的crrt液体管理对感染性休克患者预后的影响

摘要

Objective:To observe the function of patients with septic shock CRRT continuous renal re-placement therapy in PICCO liquid management of patients with clinical prognosis. Methods: All the septic shock patients admitted in our hospital from 2013 to 2016 were averaged randomly divided into two groups, re-spectively in the CRRT treatment choice conventional liquid PICOO management style and management. Re-sults:The level of lactic acid was below 2mmoL/L and the level of ScvO2≥70% on 6 hours after recovery.There was no significant difference ( P >0.05) . The liquid dosage, the dosage of phenylephrine of patients af-ter 48 hours recovery of the observation group were significantly less than the control group (P<0.05), and the time of breathing machine was less than the control group ( P<0.05); the incidence of pulmonary edema within 28 days and mortality was significantly lower than the control group (P<0.05). Conclusion: PICCO guidance of patients with septic shock fluid management can provide hemodynamic quantitative monitoring in-dicators for patients, and make for outcomes with CRRT treatment for patients, reduce drug dosage and liquid.%目的:探讨感染性休克患者CRRT持续肾脏替代治疗中以PICCO指导液体管理对患者临床预后的作用.方法:选取2013至2016年我院收治的感染性休克患者,随机平均分为两组,分别在CRRT治疗中选择常规液体管理方式与PICOO指导液体管理.结果:患者复苏后6h乳酸<2mmoL/L以及ScvO2≥70%比例差异无统计学意义(P>0.05),观察组患者48h复苏液体用量、去甲肾上腺素用量少于对照组,差异具有统计学意义(P<0.05),呼吸机时间少于对照组,差异具有统计学意义(P<0.05),肺水肿发生率与28d内死亡率低于对照组,差异具有统计学意义(P<0.05).结论:PICCO指导感染性休克患者液体管理,可以提供患者血流动力学量化监测指标,有利于患者CRRT治疗的预后,减少药物及液体用量.