L4/5棘突间植入椎间融合器的稳定性及对相邻节段的生物力学特性和生物相容性的影响

摘要

目的:探讨L4/5棘突间植入椎间融合器的稳定性及对相邻节段的生物力学特性与生物相容性的影响.方法:采集18组新鲜成人冰冻脊柱标本,其中模拟L4/5棘突间植入椎间融合器为研究组,而正常标本为对照组,两组各9例,两组标本进行编号后经棘突间弹性内植入并用固定器进行固定.结果:研究组于各个植入处在前屈、中心压缩、侧屈及后伸下的应变变化均较对照组小(P均<0.05).于施加最大载荷600N下,研究组椎体的角位移与线性位移在左侧屈、左旋转、前屈、后伸状态下均小于对照组(P均<0.05).结论:L4/5棘突间植入椎间融合器可有效改善伤椎的活动度,保留其稳定性,有助于减轻椎间盘应力.%Objective:To investigate the effects of stability of the L4/5 lumbar, biomechanical properties and biocompatibility of adjacent segments for interspinous fusion cage. Methods: 18 fresh adult frozen spine specimens were collected, including L4/5 lumbar for interspinous fusion cage as the study group, and normal specimens as the control group, with 9 specimens in each group. The specimens of two groups were numbered and implanted in vivo and fixed by fixators. Results:The strain changes in different implantation for anteflex-ion, center compression, lateroflexion and rear protraction in the study group were smaller than in the control group ( P all<0.05) . Under the maximum load of 600 N, the angular displacement and linear displacement in left lateral flexion, levorotation, anteflexion and rear protraction in the study group were lower than in the con-trol group ( P all<0.05) . Conclusion:L4/5 lumbar for interspinous fusion cage can effectively improve the ver-tebral activity and keep its stability, which is helpful to shorten the stress of the intervertebral disc.