负压封闭引流术治疗不同严重程度糖尿病足溃疡的临床价值

摘要

Objective:To investigate the clinical value of vacuum sealing drainage (VSD) in different severity of diabetic foot ulcer (DFU) by randomized controlled study.Methods: 40 cases of patients selected Wagner 2~4 grade of DFU were randomly divided into treatment group and control group, each of 20 cases.The treatment group was treated with VSD after debridement;the control group created by the method of wet dressing;4 weeks of observation, to compare the two methods of different severity of DFU clinical effect.Results: The number of days in hospital, the number of dressing changes and the number of times of dressing change and cure time were significantly shorter in the observation group than in the control group, the difference was statistically significant (P < 0.05).The total effective rate of the observation group was 100.0%, which was significantly higher than that of the control group of 80.0%, the difference was statistically significant (P < 0.05).Conclusion:DFU using (VSD) basically to avoid major amputation and achieve guaranteed toe salvage and to retain the ability of action;VSD surgery treatment at all different severity of DFU effect is significant, hospitalization time and frequency of changing dressings reduce, and the total cost of health care has no advantage.%目的:通过随机对照研究探讨负压封闭引流技术(VSD)在不同严重程度糖尿病足溃疡(DFU)的临床应用价值.方法:入选Wagner2~4级的糖尿病足溃疡患者40例,随机分治疗组和对照组各20例;治疗组清创后采用VSD;对照组清创后采用湿性换药的方法;观察4周,比较两种方法对不同级别DFU的临床作用.结果:观察组住院天数、住院换药次数和门诊换药次数以及治愈时间较对照组明显缩短,差异均有统计学意义(均P<0.05).观察组的总有效率是100.0%,较对照组的80.0%更高,差异有统计学意义(P<0.05).结论:DFU清创后使用负压封闭引流术(VSD),基本避免大截肢,实现保趾保肢和保留行动能力;负压封闭引流术治疗各级糖尿病足溃疡的效果是显著的,住院天数和换药次数减少,而医疗总费用无优势.