不同强度有氧运动对胃癌患者癌因性疲乏及血清皮质醇激素水平的影响

摘要

目的 研究不同强度有氧运动对胃癌患者癌因性疲乏及血清皮质醇激素水平的影响.方法 选取诊治的96例胃癌患者,根据有氧强度不同分为A组(20% VO2max组)32例、B组(50% VO2max组)32例及C组(60% VO2max组)32例,比较3组患者干预前和干预后2周、4周及8周时的MFSI-SF量表、RPFS量表评估结果及血清皮质醇激素水平.结果 干预前3组患者的MFSI-SF量表、RPFS量表评估结果及血清皮质醇激素水平比较,差异无统计学意义(P＞0. 05);干预后2周、4周及8周B组的MFSI-SF量表及RPFS量表评估结果均好于A组和C组,血清皮质醇激素水平均好于A组,差异有统计学意义(P＜0. 05).结论 50% VO2max的有氧运动对胃癌患者癌因性疲乏及血清皮质醇激素水平的影响相对更好,在胃癌患者中的应用价值相对更高.%Objective To investigate the effects of different intensities of aerobic exercise on cancer related fatigue and serum levels of cortisol hormone of patients with gastric cancer. Methods A total of 96 patients with gastric cancer who were diagnosed and treated in our hospital were enrolled in the study. These patients were divided into group A (20% VO2max group,n=32),group B (50% VO2max group,n=32) and group C (60% VO2max group,n=32)according to the differences intensities of aerobic exercise. Then the intervention effects before intervention and at 2w. 4w,8w after intervention were evaluated by means of MFSI-SF scale and RPFS scale, moreover, the serum levels of cortisol hormone were observed and compared among the three groups. Results Before intervention there were no significant differences in the evaluation results of MFSI-SF scale and RPFS scale as well as serum levels of cortisol hormone among the three groups (P＞0. 05),moreover, the evaluation results of MFSI-SF scale and RPFS scale at 2w,4w,8w after intervention in group B were superior to those in group A and group C,however, the serum levels of cortisol hormone in group A were superior to those in group A (P＜0. 05). Conclusion The effects of 50% VO2max aerobic exercise on cancer related fatigue and serum levels of cortisol hormone in patients with gastric cancer are relatively better,and its application is relatively higher.