首页> 中文期刊> 《河北医药》 >内听动脉、上级动脉直径和血脂水平与突发性耳聋治疗及预后的关系研究

内听动脉、上级动脉直径和血脂水平与突发性耳聋治疗及预后的关系研究

         

摘要

Objective To investigate thre correlation between the internal auditory artery, superior artery,blood lipid level and the treatment as well as prognosis of sudden deafness. Methods Fifty-nine patients with sudden deafness were enrolled as experiment group,at the same time, 78 healthy volunteers were enrolled as control group. The the serum levels of total cholesterol ( CHO) were detected,moreover, the diameters of internal auditory artery ( IAA) ,anterior inferior cerebellar artery ( AICA) ,basilar artery ( BA) were measured by magnetic resonance imaging. In addition the levels of IAA,AICA,BA and serum levels of CHO at different time points were observed and compared between the two groups. Results The diameters of IAA,AICA,BA in control group were significantly higher than those in experiment group,however,the serum levels of CHO were significantly lower than those in experiment group (P <0. 05). There were significant differences in the diameters of IAA,AICA,BA and serum levels of CHO at different time points in experiment group (P <0. 05). Moreover there were significant differences in the diameters of IAA and BA between the patients with good prognosis and the patients with poor prognosis (P<0. 05). Conclusion The patients with the increase of diameters of IAA,AICA,BA have better prognosis, which can provide objective basis for the treatment and prognosis of patients with sudden deafness.%目的 探讨内听动脉、上级动脉和血脂水平与突发性耳聋治疗及预后的关系.方法 选取59例突聋患者为试验组,同时选取同一时期听力正常健康志愿者78例为正常组,收集血液标本,测定血清总胆固醇(CHO)水平,采用磁共振成像技术测定内听动脉(IAA)、小脑前下动脉(AICA)、基底动脉(BA)直径.比较突聋患者治疗不同时间点、预后期间IAA、AICA、BA及血清CHO水平的差异.结果 正常组IAA、AICA、BA直径高于试验组,CHO低于试验组,差异有统计学意义(P<0.05).治疗不同时间点IAA、AICA、BA及CKO水平,差异有统计学意义(P<0.05).不同预后突聋患者间IAA、BA上,差异有统计学意义(P<0.05).结论 IAA、AICA及BA直径扩大,血脂水平降低,预后较好,可以为突聋患者的治疗及预后提供客观性依据.

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