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保龄汤对老年代谢综合征胰岛素抵抗的影响

     

摘要

Objective To observe the clinical efficiency of Baoling decoction on elderly insulin resistance of metabolic syndrome (MS). Methods 60 cases of MS in elderly people were randomly divided into the treatment group ( n = 30), which was treated with Baoling decoction combined with foundation treatment including control of blood pressure and glucose for 12 weeks, and the control group (n =30) , which was treated with foundation treatment for 12 weeks. The value of HOMA - IR, body mass index (BMI) and waist circumference (WC) were observed before and after treatment. Results After treatment the value of HOMA - IR, BMI and WC was significantly decreased in the treatment group and the difference between two groups was significant on HOMA - IR, BMI and WC (P<0.01). There was no statistically difference between before and after treatment on HOMA -IR, BMI and male WC in control group (P >0. 05). There was difference between before and after treatment on female WC in control group (P <0.05). Conclusion Baoling decoction combined with conventional treatment can obviously decrease the value of HOMA - IR, BMI and WC in elderly MS, which indicate that Baoling decoction may improve insulin resistance of MS in the old.%目的 观察保龄汤对老年代谢综合征(MS)患者胰岛素抵抗的干预作用.方法 将60例MS患者随机分为2组.治疗组30例在控制血压、血糖等治疗基础上予保龄汤治疗,对照组30例子控制血压、血糖等基础治疗.治疗12周后比较2组胰岛素抵抗指数(HOMA-IR)、体质量指数(BMI)及腰围(WC)情况.结果 治疗组治疗后HOMA-IR、BMI及WC明显下降,与本组治疗前及对照组治疗后比较差异均有统计学意义(P<0.01);对照组治疗后HOMA-IR有所下降,但与治疗前比较差异无统计学意义(P>0.05),BMI及男性WC无明显变化(P>0.05),女性WC高于治疗前(P<0.05).结论 保龄汤结合基础治疗能够明显降低老年MS患者HOMA-IR、BMI及WC,表明保龄汤能够缓解老年MS患者的胰岛素抵抗.

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