慢性丙型肝炎患者血清HCV RNA水平与AST/ALT比例的关系

摘要

目的 分析抗-HCV阳性患者血清水平HCV RNA与AST/ALT活性的关系;评价AST/ALT比值,HCV RNA水平在判断丙肝患者预后方而的价值.方法 采用ELISA法检测抗-HCV,阳性标本分别用荧光PCR试剂盒测定HCV RNA;全自动生化分析仪检测AST/ALT.结果 78份抗-HCV阳性标本经PCR检测后有31份标本含有HCV RNA,HCV RNA拷贝量与AST/ALT比例呈正相关.结论 动态监测AST/ALT比例和HCV RNA的水平,可用于丙型肝炎的预后估计.%To investigate the relationship between serum hepatitis C virus RNA and the ratio of aspartate aminotransferase to alanine aminotransferase (AST/ALT ratio) in anti-HCV positive samples of patients, and assess the prognostic validity of the ratio of AST/ALT, HCV-RNA in patients with chronic liver disease. Methods Hepatitis C virus fluorescence PCR diagnostic kit was carried out on the anti-HCV positive samples; the ratio of serum AST/ALT was measured by biochemical instrument. Results Of 78 cases, 31 were positive for HCV RNA,the copies of HCV-RNA has correlation with the ratio of AST/ALT. Conclusion The ratio of AST/ALT and the copies of HCV-RNA can be dynamic measured to estimate the prognosis of HCV.