目的：探讨磁共振弥散加权成像及T2加权像对肝脏局部病灶病变诊断的准确性。方法将57例肝占位患者根据病理结果分为良性组和恶性病变组，应用磁共振弥散加权成像及T2加权像对病变部位的弥散系数进行计算，观察其诊断准确性。结果①肝囊肿、血管瘤和肝恶性肿瘤(包括肝细胞癌和转移性肿瘤)三者之间平均弥散系数差异具有统计学意义(P<0.05)；而肝细胞癌和转移性肿瘤两者平均弥散系数差异无统计学意义(P>0.05)。表面弥散系数诊断恶性肿瘤的敏感性为85.7%(24/28)，特异性为97.8%(44/45)，诊断准确性为93.2%(68/73)；②血管瘤和囊肿T2平均值明显高于恶性病变，差异有统计学意义(P<0.05)。T2值诊断的敏感性为80.0%(24/30），特异性为91.7%(44/48)，诊断准确性为87.2%(68/78)。结论磁共振弥散加权成像利用平均弥散系数差异和T2加权像能够提高局灶病变诊断的准确性。%Objective To explore the accuracy of diffusion weighted magnetic resonance imaging and T2 weighted imaging in the diagnosis of focal liver lesion. Methods Fifty-seven patients of liver lesions were divided into benign group and malignant group according to the pathological results. The diffusion coefficient of the lesion was calculated using diffusion-weighted magnetic resonance imaging and T2 weighted imaging. The diagnosis accura-cy of focal liver lesions were observed. Results The liver cyst, hemangioma and hepatic malignant tumors (includ-ing hepatocellular carcinoma and metastatic tumor) showed statistically significant difference in average diffusion co-efficient (P<0.05), while there was no significant difference in the average diffusion coefficient between hepatocellu-lar carcinoma and metastatic tumor (P>0.05). The sensitivity of the surface diffusion coefficient was 85.7% (24/28) for diagnosis of malignant tumor, and the specificity was 97.8%(44/45), with diagnostic accuracy of 93.2%(68/73). The T2 average value of hemangioma and liver cyst was significantly higher than that of malignant lesions (P<0.05). The diagnosis sensitivity of T2 value was 80.0% (24/30), and the specificity and diagnostic accuracy were 91.7%(44/48) and 87.2%(68/78). Conclusion Diffusion weighted magnetic resonance imaging using the average diffusion coefficient difference and T2 weighted imaging can improve the diagnostic accuracy of focal lesions.
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