高血压病已成为老年人群最常见、患病率最高的慢性心血管疾病，其通过损伤血管壁的结构和功能参与动脉粥样硬化的发生、发展。老年人、高血压都是动脉粥样硬化性疾病的危险因素，老年人血压波动大、昼夜节律变化明显、脉压增大，这些均为发生动脉粥样硬化的危险因素。高血压病患者大动脉硬化程度的评价已成为当今高血压病防治的热点。对于评估动脉僵硬度的指数，脉搏波传导速度(PWV)的测量可以反映动脉弹性的早期变化。PWV是评估动脉弹性和血管功能变化的简捷、有效且可重复的非侵入性指标。PWV与动脉粥样硬化及高血压所致的血管病变高度正相关，并且可作为成人冠心病病死率的强预测因子。%Hypertension has become the most common and highest prevalence of chronic cardiovascular dis-ease in the elderly. It is involved in the occurrence and development of atherosclerosis through the structure and function of the damaged vessel wall. The elderly and the hypertension are the risk factors of atherosclerotic disease. Moreover, the elderly people's blood pressure fluctuations, changes in circadian rhythm, and pulse pressure are the risk factors for atherosclerosis. Evaluation of the degree of hypertension in patients with hypertension has become a hot spot in the pre-vention and treatment of hypertension. In terms of the index for the assessment of arterial stiffness, the measurement of pulse wave velocity (PWV) can reflect the early changes of arterial elasticity. PWV is a simple, effective and repeatable non-invasive index for evaluating the changes of arterial elasticity and blood vessel function, which is highly positively correlated with atherosclerosis and vascular disease, and can be used as a strong predictor of mortality of coronary heart disease in adults.
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