光叶兔儿风的化学成分研究

摘要

To investigate the chemical constituents of Ainsliaea glabra ,several chromatographies including Silica gel column chromatography and Sephadex LH-20 gel column chromatography were applied to the isolation and purifica-tion of chemical constituents.The structures were identified on the basis of chemical evidence and spectral data.The results showed that seventeen compounds were isolated from A .glabra and they were identified as taraxasteryl ace-tate(1),dotriacont-1-ene(2),β-sitosterol(3),chrysophanol(4),lupenyl palmitate(5),methyl linolenate(6),linoleic acid(7),phytol(8),stigmast-4-en-3-one(9),phytenal(10),betulinic acid(11),(9Z,11E)-13-oxo-9,11-ocatadecadieno-ic acid(12),E-7,9-diene-11-methenyl palmitic acid(13),taraxinic acid(14),3β-hydroxy-cholesta-5-ene(15),epoxyly-copaene(16),28-O-laurylbetulin(17).Compounds 1-17 were obtained from this herb for the first time.%利用正反相硅胶、凝胶(Sephadex LH-20)等多种柱色谱法,对光叶兔儿风化学成分进行分离纯化,并根据理化性质和波谱数据进行结构鉴定。结果表明：已分离得到17个化合物,分别鉴定为蒲公英甾醇乙酸酯(1),三十二碳烯(2),β-谷甾醇(3),大黄酚(4),扇醇棕榈酸酯(5),亚麻酸甲酯(6),亚油酸(7),植物醇(8),[24S]-豆甾-4烯-3-酮(9),植物烯醛(10),白桦脂酸(11),13-羰基-十八碳二烯酸(12),E-7,9-11-羰基-棕榈酸(13),蒲公英酸(14),3β-羟基-胆甾-5-烯(15),环氧树脂烯(16),28-O-月桂酸酯白桦醇(17)。化合物1~17均为首次从该植物中分离得到。