目的通过对各类β-内酰胺类药物相互交叉过敏反应相关性研究，找寻各类β-内酰胺类药物相互交叉过敏反应比率。为临床合理选择β-内酰胺类药物提供理论依据。方法通过对在2011年3月至5月期间住院的有β-内酰胺类抗生素过敏患者进行调查，对结果进行回顾性统计分析。结果青霉素与头孢类抗生素发生交叉过敏的的概率较低；头孢类抗生素与其他β-内酰胺类药物相互交叉过敏反应的概率相对较高。结论对于有青霉素过敏的患者且头孢皮试阴性的患者，使用头孢类抗生素是安全的。% Objective Though the correlation studies of all kinds of beta beta-lactamase-producing drugs overlapping allergic reaction, to find all kinds of beta beta-lactamase-producing drugs overlapping allergic reaction ratio. For clinical rational choice beta beta-lactamase-producing provide theoretical basis of drugs. Methods Based on the march in 2011 to five months in the hospital there are beta beta-lactamase-producing class antibiotic allergy patients to survey, statistics and analysis results. Results With cephalosporin antibiotic penicillin allergies to the probability of happened cross low; Cephalosporin antibiotic and other beta beta-lactamase-producing drugs overlapping the probability of an allergic reaction are relatively high. Conclusion Patients with penicillin allergies and skin test negatie patient cephalosporins, use cephalosporin antibiotic is safe.
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