目的：观察用枳术宽中胶囊治疗脑梗死后便秘的临床疗效。方法156例脑梗死伴便秘患者被随机分为治疗组和对照组两组。两组均按原治疗方案治疗脑梗死，药物及治疗措施相同，治疗组患者另给予枳术宽中胶囊口服，每次3粒，每日3次。对照组给予西沙必利治疗，每次10mg，每日3次口服。两组均用2周。结果治疗组104例中，显效39例，有效57例，无效8例，总有效率为92.31%；对照组52例中显效20例，有效25例，无效7例，总有效率86.54%，两组总有效率差异无显著性（χ2=0.747，P>0.05）。但治疗组在排便习惯、便质干结、排便困难3项症状的起效时间和恢复正常时间均优于对照组（P<0.05），无明显不良反应。结论用枳术宽中胶囊治疗脑梗死并发便秘能润肠通便，促进胃肠运动，改善精神状态，有利于神经功能恢复。%Objective To observe the clinical curative effect of treating cerebral infarction with constipation after Zhizhukuanzhong capsules. Methods 156 cases of cerebral infarction with constipation patients were randomly divided into treatment group and control group two groups. Two groups according to the treatment of cerebral infarction and primary treatment, drug treatment, patients in the treatment group were given oral other Zhizhukuanzhong capsule, 3 capsules each time, 3 times a day. The control group was given cisapride, 10mg each time, 3 times a day. The two groups were 2 weeks. Results The treatment group of 104 cases, 39 cases markedly effective, effective 57 cases, invalid 8 cases, the total efficiency of 92.31%;control group 52 cases, 20 cases markedly effective, effective 25 cases, invalid 7 cases, the total efficiency of 86.54%, the total efficiency of two groups had no significant difference (χ2=0.747, P>0.05). The onset time but the treatment group in bowel habits, then dry, difficult defecation 3 symptoms and restore the normal time was better than the control group (P<0.05 ), no significant adverse reactions. Conclusion The use of Zhizhukuanzhong capsules in treatment of cerebral infarction complicated with constipation can catharsis, promote gastrointestinal motility, improve mental state, is beneficial to the recovery of neural function.
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