目的 研究分析不同血脂指标对于我国中年人群缺血性心血管疾病事件的预测作用。方法选择住院、门诊、社区及体检人群资料完整的10200人作为研究对象。所有被研究者的平均随访时间为（15.8±2.1）年。观察缺血性心血管疾病事件，其包括冠心病以及缺血性脑卒中。结果在随访期间出现缺血性心血管疾病（ICVD）事件有372例，其中单纯冠心病94例，缺血性脑卒中267例，冠心病合并缺血性脑卒中11例。人群血清总胆固醇水平与ICVD发病呈现出正相关关系，但是HDL-C水平与ICVD发病有负相关关系，但没有统计学意义。结论我国中年人群的血脂水平明显低于西方人群，血清TC、LDL-C以及NHDL-C以及TC/HDL-C水平升高对于ICVD发病具有独立预测的作用，控制血脂在正常的水平下可以有效减少人群中ICVD的发病率，具有比较重要的意义。%Objective To study the analysis of different lipids index for prediction function in middle-aged Chinese ischemic cardiovascular events. Methods The heart and lung disease epidemiology research data of population 10200 people as the research object, all the mean follow-up time was researchers for (15.8±2.1) years. To observe the event of ischemic cardiovascular diseases, including coronary heart disease and ischemic stroke. Results The emergence of ischemic cardiovascular disease during the follow-up period ( ICVD ) events in 372 cases, only 94 cases of coronary heart disease, 267 cases were ischemic stroke, coronary heart disease and ischemic stroke in 11 cases. Serum total cholesterol levels and the pathogenesis of ICVD showed a positive correlation, but a negative correlation between HDL-C levels and the pathogenesis of ICVD, but no statistical significance. Conclusion The serum lipid levels in middle-aged Chinese was significantly lower than that of Western populations, elevated serum levels of TC, LDL-C and NHDL-C and TC/HDL-C level is independently predictive role in the pathogenesis of ICVD, lipid control can effectively reduce the incidence rate of ICVD in normal level, has important significance.
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