儿科耐甲氧西林金黄色葡萄球菌医院感染的因素分析

摘要

Objective To investigate the factors of pediatric hospital infection caused by methicillin-resistant staphylococcus aureus (MRSA). Methods A retrospective analysis of clinical data on 387 cases of children admitted to our hospital from Jan 2011 to Feb 2012 was made. The factors of pediatric hospital infection caused by MRSA were analyzed. Results Bacteria from 387 specimens were isolated and identified. 356 strains of staphylococcus aureus, 168 strains were MRSA, accounting for 47.19%. Age, time of antimicrobial use and hospitalization time were related to hospital infection caused by MRSA (P<0.05), while ratio of boys and girls was not related to MRSA(P>0.05). Conclusion Shorten the length of hospital stay and time of antimicrobial agents use, as well as pathogen monitoring are effective measures for prevention of MRSA infection.%　　目的探讨儿科耐甲氧西林金黄色葡萄球菌（MRSA）医院感染的因素。方法回顾性分析我院儿科2011年1月至2012年2月收治的住院患儿387例的临床资料，对其中检出的 MRSA 医院感染患儿进行感染因素分析。结果387例患儿的标本经细菌的分离与鉴定，分离出金黄色葡萄球菌356株，检出 MRSA 168株，检出率为47.19%，年龄、抗菌药物使用时间、住院时间与 MRSA 医院感染相关，患儿中男女童例数与 MRSA 医院感染无明显相关（P>0.05）。结论预防医院感染 MRSA 的有效措施是尽量缩短住院时间及使用抗菌药物时间，对小儿积极进行病原学监测，及时发现和隔离 MRSA 感染。