目的探讨益母草注射液配合宫腔填塞纱条在剖宫产术中治疗前置胎盘产后出血的可行性、有效性及安全性.方法回顾性分析2007年1月至2011年12月在河南大学附属郑州市第一人民医院确诊为前置胎盘(中央性、部分性)的80例患者的临床资料,观察组40例采用益母草注射液配合宫腔纱条填塞,对照组40例采用欣母沛配合宫腔纱条填塞治疗剖宫产产后出血,观察对比产后2h、产后24h阴道出血情况.结果观察组患者全部抢救成功,其中38例(95%)止血效果满意,2例(5%)宫腔填塞纱条失败,行子宫切除术.对照组39例(97.5%)止血效果满意,1例(2.5%)失败,行子宫切除术.两组产后2h、24h阴道出血量、疗效及不良反应比较,差异无统计学意义(P>0.05).两组住院费用相比有统计学意义(P<0.05).结论益母草注射液配合宫腔填塞纱条在剖宫产术中治疗前置胎盘产后出血是一种操作简单、安全、有效、价廉的方法.%Objective To investigate the feasibility, efficacy and safety of motherwort injection combined with intrauterine packing in controlling of postpartum hemorrhage of cesarean section with placenta previa. Methods Retrospectively analyze the clinical date of 80 patients with placenta previa (central placenta previa, partrial placenta previa) in Henan university affiliated first people's hospital of zhengzhou from January 2009 to December 2011. In order to control massive hemorrhage during cesarean section, patients in the study group (40 cases) received mortherwort injection combined with intrauterine packing, patients in the control group (40 cases) received carboprost tromethamine injection combined with intrauterine packing. The amount of vaginal bleeding during 2 hours after delivery and 24 hours after delivery were observed. Results Patients in the study group were all successfully salvaged, in which 38 cases (95%) were successful in controlling of massive hemorrhage, 5 cases (5%) were failed and hysterectomy was used. In the control group, 39 cases (97.5%) were successful in controlling of massive hemorrhage, 1 cases (2.5%) were failed and hysterectomy was used. The two groups were no statistical difference in the amount of vaginal bleeding, efficacy and adverse reactions. The cost of hospital stay was statistical difference (P<0.05). Conclusion Motherwort injection combined with intrauterine packing is a simple, safe, effective and inexpensive technique in controlling of postpartum hemorrhage of cesarean section with placenta previa.
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