Objective To investigate the effect of of pantoprazole combined with pituitrin on the treatment of liver cirrhosis complicated with upper gastrointestinal hemorrhage. Methods 200 patients with liver cirrhosis complicated with upper digestive tract hemorrhage were selected and randomLy divided into observation group and control group. The control group was treated with pituitrin, the observation group were given pantoprazole combined with pituitrin. The effectiveness of the two groups after treatment was evaluated. The hemostasis time and hospitalization time were recorded. Results The total effective rate in the observation group was signiifcantly higher than that in the control group, and the difference was statistically signiifcant (P<0.05). The hemostasis time in the observation group compared with that in the control group, he difference was statistically signiifcant (P<0.05). The time of hospitalization in observation group compared with that in the control group, he difference was statistically signiifcant (P<0.05). Conclusion The clinical effect of pantoprazole combined with pituitrin in treatment of liver cirrhosis complicated with upper gastrointestinal hemorrhage is signiifcant, and which is worthy of reference.%目的：探讨泮托拉唑联合垂体后叶素治疗肝硬化合并上消化道出血的临床效果。方法选择200例肝硬化合并上消化道出血患者，随机分为观察组和对照组。对照组患者给予垂体后叶素，观察组给予泮托拉唑联合垂体后叶素治疗。评定两组治疗效果。记录两组止血时间和住院时间。结果观察组止血效果总有效率高于对照组止血效果总有效率，差异有统计学意义（P<0.05）。观察组患者止血时间和对照组止血时间比较，差异有统计学意义（P<0.05）。观察组住院时间和对照组住院时间比较，差异有统计学意义（P<0.05）。结论泮托拉唑联合垂体后叶素治疗肝硬化上消化道出血的临床效果显著，值得借鉴。
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