目的 探讨高黏度骨水泥在治疗骨质疏松性椎体压缩性骨折中的临床疗效分析.方法 随机选取本院2012年1月-2016年1月收治的80例骨质疏松椎体压缩性骨折患者.将患者随机分为对照组和观察组,每组各40例,均采用骨水泥联合经皮椎体后凸成形术治疗,对照组采用低黏度骨水泥,观察组采用高黏度骨水泥.采用视觉模拟量表(VAS)评分比较手术前后患者疼痛情况,Oswestry指数(Oswestry disability index,ODI)评分评估患者腰背部功能.观察并比较两组患者VAS、ODI评分,骨水泥渗漏及相关并发症情况.结果 所有患者均顺利完成手术,术后随访1年以上,期间未发生严重并发症.所有患者VAS评分,ODI评分均明显高于术前.两组均出现骨水泥渗漏及其他并发症,低黏度骨水泥组骨水泥渗漏率为66.7%,明显高于高黏度骨水泥组的33.3%,P<0.05,但均无明显神经功能损伤.结论 高黏度骨水泥在骨质疏松椎体压缩性骨折中的应用能显著改善患者临床疗效,明显降低骨水泥渗漏及并发症的发生率.%Objective To investigate the clinical effect of high viscosity bone cement for treatment of osteoporotic vertebral compression fractures.Methods From Jan.2012 to Jan.2016, 80 patients with osteoporosis vertebral fractures were enrolled into this study.They were randomly divided into control group and observation group, with 40 cases in each group.They were all adopted PKP methods for treating, while the observation group got the high viscosity bone cement and the control group got the low one.Clinical outcomes were assessed in terms of back pain visual analogue scale (VAS), Oswestry disability index (ODI) after surgery.The outcomes of back pain VAS score, ODI, venous leakage rate, discoidal leak rate, rate of around vertebral body, rate of contiguous vertebral fracture were compared between two groups.Results All patients were successfully completed surgery.We took postoperative follow-up more than one year, there were severe complications occurred.VAS score, ODI score were significantly higher than that of before operation.Two groups had both bone cement leakage and other complications.Low viscosity bone cement group of bone cement leakage rate was 66.7%, significantly higher than the 33.3% of the high viscosity of bone cement group, P<0.05, but no obvious neurologic injury.Conclusion The high-viscosity bone cement for osteoporotic vertebral fractures provides better clinical outcomes.It may reduce bone cement leak rate and complications.
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