甲状腺微小乳头状癌颈部中央区淋巴结转移的临床特点分析

摘要

目的 分析甲状腺微小乳头状癌(PTMC)颈部中央区淋巴结转移的临床特点及影响因素.方法 回顾性分析249例PTMC患者的临床资料,探讨PTMC患者颈部中央区淋巴结转移的临床特点及影响因素.结果 PTMC患者颈部中央区淋巴结转移率为39.8%(99/249).单因素、多因素分析结果均显示,年龄<45岁、肿瘤多灶、肿瘤直径>5 mm、肿瘤穿透被膜是影响颈部中央区淋巴结转移的危险因素.结论 PTMC患者颈部中央区淋巴结转移率较高,对于年龄<45岁、肿瘤多灶、肿瘤直径>5 mm、肿瘤穿透被膜的患者更应警惕中央区淋巴结转移的可能.%Objective To analyze the clinical characteristics and influencing factors of intermediate-cervical lymph node metastasis of papillary thyroid microcarcinoma ( PTMC) .Methods Clinical data of 249 patients with PTMC were analyzed retrospectively to investigate the clinical characteristics and influencing factors of intermediate-cervical lymph node metastasis in patients with PTMC .Results The rate of intermediate-cervical lymph node metastasis was 39.8%(99/249) in patients with PTMC.The results of univariate and multivariate analysis showed that age<45 years,multifocal tumor,tumor diameter >5 mm,and extranodal extension were the risk factors influencing intermediate-cervical lymph node metastasis.Conclusion The rate of intermediate-cervical lymph node metastasis is quite high among patients with PTMC.We should be alert to patients with age<45 years,multifocal tumor,tumor diameter >5 mm,and extranodal extension for the possibility of intermediate-cervical lymph node metastasis .