Objective To retrospectively review the risk factors associated with early complications following radi -cal cystectomy and orthotopic diversion .Methods The clinical data of 73 patients who had undergone orthotopic diver-sion from January 2014 to December 2015 in the Second Affiliated Hospital of Kunming Medical University were analyzed . According to the Postoperative Complication Grading System , in-hospital complications were retrospectively analyzed and subdivided into different grades and categories .Multivariate logistic regression was applied for correlation analysis .Results Among the 73 patients, 42 (57.5%) developed at least 1 postoperative complication .In the total of 77 of early compli-cations, 29 (37.7%) were minor complications, 44 (57.1%) were moderate complications and 4 (5.2%) were major complications.The most common complications were infection -related events, gastrointistinal events and urine leakage . According to the logistic regression analysis , the risk factors leading to postoperative complications were BMI score ( OR=1.574, P=0.002), blood loss (OR=1.050, P=0.027) and CCI score (OR=1.127,P=0.040).Conclusion The rate of severe and lethal complications following radical cystectomy and orthotopic diversion is acceptably low .The inci-dence of the early complications is correlated with BMI score , blood loss and CCI score .%目的 探讨膀胱全切原位尿流改道术后早期并发症及相关危险因素.方法 回顾性分析73例行膀胱全切原位尿流改道术患者的术后早期并发症发生情况,采用"手风琴式"并发症分级系统进行分析,并应用logistic回归分析研究其相关危险因素.结果 73例患者中出现早期并发症者42例(57.5%),共发生并发症77例次.其中轻度29例次(37.7%),中度44例次(57.1%),重度4例次(5.2%).常见的早期并发症为感染相关并发症、胃肠道相关并发症以及尿漏.logistic多因素回归分析结果显示,与患者术后早期并发症发生有关的因素有体质指数(BMI)(OR=1.574,P=0.002)、手术失血量(OR=1.050,P=0.027)和CCI评分(OR=1.127,P=0.040).结论 膀胱全切原位尿流改道术后早期轻、中度并发症发生率较高.患者BMI、术中出血量和CCI评分与其密切相关.
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